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Thermofisher·1 hour ago
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FSP Senior Scientist - Bioanalytical LCMS Chemist

San Diego, United States of AmericaMid · 5-8 years

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About this role

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

Join us as Senior Scientist!

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Our PPD® Laboratory Services team has a direct impact on improving patient health through the expertise of scientists, industry thought-leaders and therapeutic experts. As the world leader in serving science, our laboratory professionals bring their commitment to accuracy and quality to deliver groundbreaking innovations.

As a Senior Scientist, your role will be to conduct advanced diagnostic tests, ensure the highest accuracy and reliability of laboratory data, mentor junior scientists, and drive continuous improvements in laboratory methodologies and quality standards.

What You’ll Do:
Supports early drug discovery efforts through LCMS applications. Provides consistent bioanalytical support across multiple programs at various stages of drug development. Operates analytical instrumentation, provides benchtop sample processing, and regularly performs and validates bioanalytical assays. Responsible for documenting protocols, maintaining attention to detail, and presenting clear written and verbal.

Education and Experience:
• Bachelor's degree or equivalent and relevant formal academic / vocational qualification
• Previous experience to provide the knowledge, skills, and abilities to perform the job (comparable to 4-6 years).

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

  • Performs routine and exploratory bioanalytical assays to support in vitro and/or in vivo efforts
  • Supports a range of activities, including LC-MS instrument operation, maintenance, and troubleshooting  
  • Assists in assay development, method qualification, optimization, and exploratory studies
  • Interacts with in vitro/in vivo team to learn various aspects of drug discovery and provide bioanalytical support
  • Tracks and documents instrument and assay performance
  • Provides accurate documentation of protocols in ELN, in addition to frequent verbal data summaries
  • Other duties as assigned
  • Hands-on experience operating and troubleshooting UPLC-MS systems (Chromeleon, Agilent preferred)
  • Familiarity with High Resolution, qTime of Flight, and/or Triple Quad MS systems (Thermo, Agilent)
  • Ability to interpret chromatographic and mass spectrometry data (small molecule focus, protein/peptide beneficial)
  • Competency to perform assays consistently, efficiently and identify issues if presented
  • Ability to recognize patterns or inconsistencies in data and instrumentation
  • Ability to work individually and as part of a team
  • Good computer skills, knowledge of Excel, Powerpoint
  • Good communication, problem-solving, analytical thinking, planning and organizational skills
  • Understands importance of data accuracy and balancing deadlines
  • Collaborative and highly motivated
  • Ability to keep accurate records
  • Academic and/or working knowledge of analytical chemistry, chromatography, mass spectrometry, molecular biology, in vitro biological assays


Working Conditions and Environment:
• Work is performed in a laboratory and/or a clinical environment with exposure to electrical office equipment.
• Occasional drives to site locations, occasional domestic travel.
• Exposure to biological fluids with potential exposure to infectious organisms.
• Rare exposure to skin and lung irritants, radiation, toxic materials and hazardous waste.
• Personal protective equipment is required such as protective eyewear, garments and gloves.
• Exposure to fluctuating and/or extreme temperatures on rare occasions.

Physical Requirements:
• Ability to work in an upright and /or stationary position for 6-8 hours per day.
• Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment.
• Occasional mobility needed.
• Occasional crouching, stooping, with frequent bending and twisting of upper body and neck.
• Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs.
• Ability to access and use a variety of computer software developed both in-house and off-the-shelf.
• Ability to communicate information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences.
• Frequently interacts with others to obtain or relate information to diverse groups.
• Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals. Requires multiple periods of intense concentration.
• Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence. Ability to perform under stress. Ability to multi-task.
• Regular and consistent attendance.

Why Join Us?
When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience – and where your contributions truly make a difference.

Apply today to help us deliver tomorrow’s breakthrough.

Compensation and Benefits

The salary range estimated for this position based in California is $91,000.00–$95,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs

  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement

  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

  • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

H1B sponsor likely
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