EVA Pharma is hiring Senior Scientist for the inhalation development team. The role will be responsible for hands-on formulation development, analytical characterisation, scale-up, and process validation of Generic Dry Powder Inhaler products — including capsule-based, blister-based, reservoir-based, dual capsule/blister inhalers, and generic nebulizers.
The role requires deep technical expertise in powder engineering and inhalation science, with the ability to independently drive development activities.
Key responsibilities:
DPI Formulation Development
- Design and optimise DPI, MDI & Nebulizer formulations for capsule-based, blister-based, reservoir-based, and dual capsule/blister inhalers
- Develop and evaluate device-formulation compatibility across all inhalation platform types
- Apply particle engineering techniques — micronization, spray drying, powder blending — to achieve target aerodynamic profiles
- Develop generic nebulizer formulations alongside DPI programmes
- Execute feasibility, prototype, and optimisation studies with full scientific documentation
Analytical Characterisation
- Perform aerodynamic characterisation using NGI and DUSA for in-process and release testing
- Apply laser diffraction and other particle sizing tools to characterise powder properties
- Execute and interpret analytical data to guide formulation decisions and device selection
- Support development and qualification of analytical methods specific to inhalation products
Scale-Up & Process Validation
- Lead scale-up activities from lab to pilot and commercial manufacturing scale
- Define and optimise critical process parameters using QbD principles, DoE, and FMEA
- Execute process validation protocols and compile validation reports
- Identify and mitigate technical risks through the development lifecycle
Tech Transfer to Manufacturing
- Prepare technology transfer packages including formulation, process, and analytical documentation
- Support on-site transfer activities at manufacturing scale and resolve technical deviations
- Collaborate with production and engineering teams to ensure successful handover
Bioequivalence Support
- Contribute to bioequivalence protocol design for generic DPI products versus reference innovators
- Prepare formulation and device rationale sections required for BE study initiation
- Support interpretation of BE data from a formulation science perspective
Scientific Guidance
- Provide day-to-day technical guidance to 1–3 junior researchers working on DPI projects
- Review experimental data, troubleshoot issues, and validate scientific conclusions
- Maintain up-to-date knowledge of inhalation science, device technologies, and industry trends
Requirements
Education:
PhD or Master's degree in Pharmaceutics, Pharmaceutical Sciences, or related field
Overall Experience:
8–10 years of hands-on experience in DPI development within the pharmaceutical industry
Technical skills:
- Proven formulation experience across capsule-based, blister-based, reservoir-based, and dual DPI formats
- Hands-on expertise with NGI, DUSA, and laser diffraction for aerodynamic characterisation
- Particle engineering skills: micronization, spray drying, and powder blending
- Scale-up and process validation experience for inhalation products
- Experience preparing technology transfer documentation for manufacturing handover
- Contribution to BE protocol design or study initiation for generic DPI products
- Familiarity with QbD, DoE, and FMEA-based risk management
