Lead Systems Engineer
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What you'll do
- Partner with the Head of Systems Engineering to define SE processes, standards, tooling, and review practices across the company
- Own critical architectural decisions end to end, with authority to set direction and hold the line on margins, safety, and quality
- Act as the technical integrator across hardware, software, autonomy, operations, and pharmacy teams
- Mentor engineers across disciplines and grow systems thinking throughout the organization
- Influence roadmap and product strategy alongside executive leadership
- Define and own the system safety strategy for a fully autonomous pharmacy, from hazard analysis through a defensible safety case
- Apply Safety of the Intended Function (SOTIF) methods to identify and reduce risk from performance limitations, edge cases, and unknown-unsafe scenarios — not just component failures
- Lead hazard analyses (e.g., STPA, FMEA, FTA) spanning perception, dispensing verification, software, and human interaction
- Set safety metrics, acceptance criteria, and residual-risk arguments; build the evidence (simulation, testing, field data) that supports them
- Establish safety monitoring and incident-learning loops as the fleet grows
- Own the regulatory strategy for autonomous dispensing across state Boards of Pharmacy and relevant federal authorities
- Translate regulator objectives (patient safety, accuracy, traceability, accountability) into system requirements and verifiable evidence
What they're looking for
- 8-12+ years of engineering experience on complex, safety-critical products, including senior technical leadership of system architecture or system safety
- Track record of shipping systems with real safety, operational, and economic consequences. Direct robotics experience isn't required; we welcome candidates from autonomous vehicles, aerospace, medical devices, and industrial automation
- Deep expertise in system safety for autonomous or software-intensive systems, including SOTIF (ISO 21448) and hazard analysis methods (STPA, FMEA, FTA)
- Experience building and defending safety cases or equivalent risk arguments with external stakeholders
- Deep expertise in system architecture, requirements definition, interface design, and design trades
- Fluency across hardware, software, and operations, with depth in at least one of: autonomy/perception, embedded or distributed software, electronics, or mechatronics
- Demonstrated ability to set technical direction and influence without formal authority across teams and leadership
- First-principles thinker who is data-driven, decisive under uncertainty, and operates with high ownership and low ego
Nice to have
- Experience with autonomy and functional safety standards such as UL 4600, ISO 26262, IEC 61508, or ISO 10218
- Experience with medical device or aerospace safety frameworks (e.g., ISO 14971, IEC 62304, ARP4754A/ARP4761)
- Direct experience engaging regulators (e.g., state agencies, NHTSA, FAA, FDA, DEA, Boards of Pharmacy) on novel technology
- Experience shaping standards, policy, or regulatory frameworks for emerging technology
- Experience building an engineering function or processes at an early-stage company
- Experience scaling autonomous systems from pilot to fleet deployment
Summarised by NextRaise from the employer’s description, which follows in full below.
Full description from employer
About Us
We're Queue, the world's first fully autonomous robotic pharmacy. We go from sealed wholesale bottles to filled, verified prescription vials with zero human involvement.
We built Queue because no one should ever have to wait in line for the medicines they need. One in three US pharmacies has shut down. Pharmacists are overworked to a breaking point. And patients are paying the price. Queue fixes that. Pharmacists get to practice pharmacy again — counseling patients, catching interactions, doing the work only they can do. And patients get their prescriptions in 60 seconds or less, any time, anywhere.
We're backed by over $18 million from Alleycorp, Riot Ventures, Ubiquity Ventures, House Capital, and others who believe the pharmacy system is broken and that robotics can fix it. Queue was founded by Nick Desai (6x founder, previously CEO of Heal) and Joshua Liu (previously Tesla, Waymo, and Zipline).
About the Role
As Queue's second systems engineer, you'll be a technical leader and a true partner to the Head of Systems Engineering. You'll hold real authority over the architecture, safety, and regulatory direction of a fully autonomous system that dispenses medication to patients — with no human in the loop to catch a mistake.
This is a staff / principal level role. Together we'll build Queue's systems engineering culture: how we make decisions, how we define "safe enough," and how we prove it to ourselves, our partners, and the regulators who oversee pharmacy. You'll set the bar others work to, and your judgment will shape the company as we scale from pilot sites to nationwide deployment.
What You'll Own
Technical Leadership & Culture
Partner with the Head of Systems Engineering to define SE processes, standards, tooling, and review practices across the company
Own critical architectural decisions end to end, with authority to set direction and hold the line on margins, safety, and quality
Act as the technical integrator across hardware, software, autonomy, operations, and pharmacy teams
Mentor engineers across disciplines and grow systems thinking throughout the organization
Influence roadmap and product strategy alongside executive leadership
Autonomy Safety & SOTIF
Define and own the system safety strategy for a fully autonomous pharmacy, from hazard analysis through a defensible safety case
Apply Safety of the Intended Function (SOTIF) methods to identify and reduce risk from performance limitations, edge cases, and unknown-unsafe scenarios — not just component failures
Lead hazard analyses (e.g., STPA, FMEA, FTA) spanning perception, dispensing verification, software, and human interaction
Set safety metrics, acceptance criteria, and residual-risk arguments; build the evidence (simulation, testing, field data) that supports them
Establish safety monitoring and incident-learning loops as the fleet grows
Regulatory Strategy
Own the regulatory strategy for autonomous dispensing across state Boards of Pharmacy and relevant federal authorities
Translate regulator objectives (patient safety, accuracy, traceability, accountability) into system requirements and verifiable evidence
Represent Queue's engineering case directly with regulators, pharmacy partners, and standards bodies
Help shape emerging regulatory frameworks for pharmacy automation, working with legal, pharmacy, and business leadership
Architecture & Model-Driven Tradeoffs
Own system requirements, interfaces, and performance, reliability, and safety budgets
Build and maintain system-level models for throughput, reliability, safety, and cost; use them to drive quantitative trade studies
Resolve ambiguity through first-principles analysis and clear, well-documented decisions
Architect for scale, serviceability, and field reliability, updating assumptions as manufacturing and field data arrive
Qualifications / Experiences
Must Have:
8-12+ years of engineering experience on complex, safety-critical products, including senior technical leadership of system architecture or system safety
Track record of shipping systems with real safety, operational, and economic consequences. Direct robotics experience isn't required; we welcome candidates from autonomous vehicles, aerospace, medical devices, and industrial automation
Deep expertise in system safety for autonomous or software-intensive systems, including SOTIF (ISO 21448) and hazard analysis methods (STPA, FMEA, FTA)
Experience building and defending safety cases or equivalent risk arguments with external stakeholders
Deep expertise in system architecture, requirements definition, interface design, and design trades
Fluency across hardware, software, and operations, with depth in at least one of: autonomy/perception, embedded or distributed software, electronics, or mechatronics
Demonstrated ability to set technical direction and influence without formal authority across teams and leadership
First-principles thinker who is data-driven, decisive under uncertainty, and operates with high ownership and low ego
Nice to Have:
Experience with autonomy and functional safety standards such as UL 4600, ISO 26262, IEC 61508, or ISO 10218
Experience with medical device or aerospace safety frameworks (e.g., ISO 14971, IEC 62304, ARP4754A/ARP4761)
Direct experience engaging regulators (e.g., state agencies, NHTSA, FAA, FDA, DEA, Boards of Pharmacy) on novel technology
Experience shaping standards, policy, or regulatory frameworks for emerging technology
Experience building an engineering function or processes at an early-stage company
Experience scaling autonomous systems from pilot to fleet deployment
How We Hire
Recruiter Screen: (30 min)
Manager Interview/Technical (90 min)
Technical Interview: (60 min)
Leadership Interview: (60 min)
What We Offer
Early-stage equity in automated pharmacy dispensing at scale
Direct impact — your work helps put medication safely in patients’ hands
Small team, zero bureaucracy, high trust
Hard problems: distributed systems, safety-critical software, regulatory compliance, real-time hardware integration
Compensation & Benefits
Competitive salary
Meaningful early-stage equity
Health, 401(k), unlimited PTO
Why Join Us Now?
Impact & Growth
Direct Patient Impact: Your work will improve healthcare outcomes for millions of patients
Market Leadership: Ground-floor opportunity to define an entirely new category of healthcare technology
Technical Innovation: Work on genuinely novel problems at the intersection of AI, robotics, and healthcare
Career Acceleration: High-visibility role with significant growth potential as the company scales
Team and Culture
World-Class Team: Work alongside exceptional engineers, AI researchers, and healthcare experts
Reports to the Head of Systems Engineering with significant autonomy and influence
Innovation Focus: Culture that prioritizes breakthrough thinking and rapid experimentation
Mission-Driven: Team united around the goal of transforming healthcare through technology
Our Values
Servant Leadership: Make those around you better. We serve our teams the way Queue serves communities: 4,000 pharmacies close each year and deserts are spreading - we’re here to reverse that.
Do the Hard Things: Healthcare, hardware, and company-building are all hard. We do them anyway. Convenience for us is life-changing for those we serve.
Own Your Work: Be accountable; take pride in what you ship. Queue lives and dies by what you do - own it fully.
Default is Now: There’s never a better time than today. Default to action: what can we prove, learn, or simplify right now?
Contact: If you have any questions, please contact us at careers@queue.inc
Company
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