Principal Scientist - Oligonucleotide Design and Chemistry

We are currently hiring a Principal Scientist to lead the design and synthesis of novel oligonucleotides for therapeutic modalities. This role involves managing multiple projects and mentoring junior scientists. Ideal candidates will have extensive oligonucleotide expertise and a strong background in scientific leadership.

Skills

• oligonucleotide design
• oligonucleotide synthesis
• oligonucleotide characterization
• sirna design
• aso design
• sirna purification
• aso purification
• bioconjugation optimization
• in vitro assay design
• in vivo assay design
• troubleshooting
• impurity profiling
• laboratory instrumentation management
• chemical biology collaboration
• organic chemistry
• mentorship
• cross-functional team leadership
• scientific communication
• external collaboration
• biochemistry collaboration